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Заболевание характеризуется патологическим ростом костей, мягких тканей и внутренних органов, особенно в области лица, рук и ног [2](https://www.medicina.ru/patsientam/zabolevanija/akromegaliya/)[5](https://semeynaya.ru/directions/endokrinologiya/akromegaliya/)[8](https://www.invitro.ru/library/bolezni/32815/). \n\nАкромегалия возникает после закрытия зон роста и завершения роста организма, развивается постепенно, длится много лет [4](https://ru.wikipedia.org/wiki/%D0%90%D0%BA%D1%80%D0%BE%D0%BC%D0%B5%D0%B3%D0%B0%D0%BB%D0%B8%D1%8F)[8](https://www.invitro.ru/library/bolezni/32815/).\n\n\n\n## Причины\n**В 95–98% случаев** причиной акромегалии является **аденома гипофиза** — доброкачественная опухоль, которая вырабатывает избыточное количество СТГ [1](https://alldoctors.moscow/articles/spravochnik-zabolevaniy/akromegaliya/). Однако аденома — не единственный источник заболевания [1](https://alldoctors.moscow/articles/spravochnik-zabolevaniy/akromegaliya/). Есть и другие механизмы: \n* **Эктопическая продукция гормонов**: опухоли поджелудочной железы, лёгких, иногда — яичников и надпочечников начинают выделять вещества, имитирующие СТГ [1](https://alldoctors.moscow/articles/spravochnik-zabolevaniy/akromegaliya/). \n* **Генетические синдромы**: например, множественная эндокринная неоплазия (МЭН) [1](https://alldoctors.moscow/articles/spravochnik-zabolevaniy/akromegaliya/). \n* **Нарушения в оси гипоталамус-гипофиз**: сбой регуляции может быть следствием врождённых дефектов или воспалительных процессов [1](https://alldoctors.moscow/articles/spravochnik-zabolevaniy/akromegaliya/).\n\n## Симптомы\n**Некоторые симптомы акромегалии**: \n* **Внешние признаки**: увеличение кистей и стоп, грубые черты лица (выступающие надбровные дуги, массивный подбородок, широкие губы, разросшийся нос) [1](https://alldoctors.moscow/articles/spravochnik-zabolevaniy/akromegaliya/). \n* **Суставные и костные нарушения**: хрящевая ткань разрастается, суставы опухают, движения становятся болезненными [1](https://alldoctors.moscow/articles/spravochnik-zabolevaniy/akromegaliya/). \n* **Симптомы со стороны нервной системы**: головные боли, снижение зрения — особенно бокового, из-за давления опухоли на зрительные нервы [1](https://alldoctors.moscow/articles/spravochnik-zabolevaniy/akromegaliya/). \n* **Внутренние органы**: увеличиваются печень, почки, щитовидная железа, сердце, работа органов нарушается [1](https://alldoctors.moscow/articles/spravochnik-zabolevaniy/akromegaliya/). \n* **Эндокринные и метаболические сбои**: диабет 2 типа, устойчивая гипертония, нарушения менструального цикла, снижение либидо, эректильная дисфункция [1](https://alldoctors.moscow/articles/spravochnik-zabolevaniy/akromegaliya/). \n\n**Важно**: симптомы появляются постепенно, часто не замечаются пациентом [10](https://unclinic.ru/akromegalija-simptomy-diagnostika-lechenie/).\n\n## Диагностика\n**При появлении симптомов акромегалии следует обратиться к врачу-эндокринологу** [12](https://polyclinika.ru/tech/akromegaliya-prichiny-simptomy-lechenie/). Для выявления заболевания проводят лабораторные и инструментальные исследования [12](https://polyclinika.ru/tech/akromegaliya-prichiny-simptomy-lechenie/). Некоторые методы: \n* **Лабораторная диагностика**: анализ на ИФР-1 в крови (инсулиноподобный фактор роста-1), оральный глюкозотолерантный тест (ОГТТ) [13](https://ProBolezny.ru/akromegaliya/). \n* **Инструментальная диагностика**: МРТ головного мозга с контрастированием для визуализации аденомы гипофиза [13](https://ProBolezny.ru/akromegaliya/).\n\n## Лечение\n**Лечение акромегалии направлено на уменьшение концентрации гормона роста в крови** [12](https://polyclinika.ru/tech/akromegaliya-prichiny-simptomy-lechenie/). Некоторые меры терапии: \n* **Удаление опухоли гипофиза**, синтезирующей гормон СТГ, или прекращение её увеличения [12](https://polyclinika.ru/tech/akromegaliya-prichiny-simptomy-lechenie/). \n* **Приём медикаментозных препаратов** для снижения уровня гормона роста в крови [12](https://polyclinika.ru/tech/akromegaliya-prichiny-simptomy-lechenie/). \n* **Корректировка симптомов** заболевания [12](https://polyclinika.ru/tech/akromegaliya-prichiny-simptomy-lechenie/). \n\n**Прогноз**: при своевременном лечении прогноз для жизни благоприятный, возможно выздоровление [11](https://www.VIDAL.ru/encyclopedia/narusheniya-obmena-veshestv-endocrinoligiya/akromegaliya). 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