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Характеризуется диффузным разрастанием в лёгких соединительной ткани и образованием характерных узелков [1](https://ru.ruwiki.ru/wiki/%D0%A1%D0%B8%D0%BB%D0%B8%D0%BA%D0%BE%D0%B7)[2](https://ru.wikipedia.org/wiki/%D0%A1%D0%B8%D0%BB%D0%B8%D0%BA%D0%BE%D0%B7). Эта инородная ткань снижает способность лёгких перерабатывать кислород, что впоследствии приводит к удушью [1](https://ru.ruwiki.ru/wiki/%D0%A1%D0%B8%D0%BB%D0%B8%D0%BA%D0%BE%D0%B7)[2](https://ru.wikipedia.org/wiki/%D0%A1%D0%B8%D0%BB%D0%B8%D0%BA%D0%BE%D0%B7). \n\nСиликоз относится к профессиональным заболеваниям из-за чёткой связи между развитием патологии и условиями труда конкретного человека [1](https://ru.ruwiki.ru/wiki/%D0%A1%D0%B8%D0%BB%D0%B8%D0%BA%D0%BE%D0%B7)[2](https://ru.wikipedia.org/wiki/%D0%A1%D0%B8%D0%BB%D0%B8%D0%BA%D0%BE%D0%B7).\n\n\n\n## Причины\nЗаболевание развивается из-за длительного вдыхания пыли, содержащей свободный диоксид кремния (кремнезём) [1](https://ru.ruwiki.ru/wiki/%D0%A1%D0%B8%D0%BB%D0%B8%D0%BA%D0%BE%D0%B7)[7](https://www.teacherjournal.ru/categories/4/articles/9926)[12](https://www.KrasotaiMedicina.ru/diseases/zabolevanija_pulmonology/silicosis). Чаще всего силикоз встречается у работников горнорудной, машиностроительной промышленности и других производств, где происходит загрязнение воздуха рабочей зоны пылью диоксида кремния [1](https://ru.ruwiki.ru/wiki/%D0%A1%D0%B8%D0%BB%D0%B8%D0%BA%D0%BE%D0%B7)[2](https://ru.wikipedia.org/wiki/%D0%A1%D0%B8%D0%BB%D0%B8%D0%BA%D0%BE%D0%B7). \n\n**Факторы риска**: \n* продолжительное и интенсивное воздействие пыли (чаще всего симптомы появляются через 10–15 лет работы в условиях запылённости) [6](https://ProBolezny.ru/silikoz/); \n* высокая пылевая нагрузка (большая суммарная доза пыли, которую работник вдыхает за всё время контакта с пылью) [6](https://ProBolezny.ru/silikoz/); \n* курение [6](https://ProBolezny.ru/silikoz/); \n* генетическая предрасположенность к развитию пылевого фиброза лёгких [6](https://ProBolezny.ru/silikoz/).\n\n## Симптомы\n**В начальных стадиях** больной ощущает нехватку воздуха, особенно при физической нагрузке, боль в груди неопределённого характера, редкий сухой кашель [1](https://ru.ruwiki.ru/wiki/%D0%A1%D0%B8%D0%BB%D0%B8%D0%BA%D0%BE%D0%B7)[2](https://ru.wikipedia.org/wiki/%D0%A1%D0%B8%D0%BB%D0%B8%D0%BA%D0%BE%D0%B7). \n\n**При выраженных формах** одышка беспокоит даже в покое, боль в груди усиливается, появляется чувство давления в грудной клетке, кашель становится постоянным и сопровождается выделением мокроты [1](https://ru.ruwiki.ru/wiki/%D0%A1%D0%B8%D0%BB%D0%B8%D0%BA%D0%BE%D0%B7)[2](https://ru.wikipedia.org/wiki/%D0%A1%D0%B8%D0%BB%D0%B8%D0%BA%D0%BE%D0%B7). \n\n**Осложнения**: силикоз повышает риск развития туберкулёза, рака лёгких, хронического бронхита, аутоиммунных и нефрологических заболеваний [4](https://tradicii-spb.ru/referrals/pulmonology/silikoz/).\n\n## Диагностика\n**Диагноз ставится на основании данных рентгенографии или КТ органов грудной клетки** при наличии воздействия диоксида кремния в анамнезе [13](https://www.msdmanuals.com/ru/professional/%D0%BB%D0%B5%D0%B3%D0%BE%D1%87%D0%BD%D1%8B%D0%B5-%D0%BD%D0%B0%D1%80%D1%83%D1%88%D0%B5%D0%BD%D0%B8%D1%8F/%D1%8D%D0%BA%D0%BE%D0%BB%D0%BE%D0%B3%D0%B8%D1%87%D0%B5%D1%81%D0%BA%D0%B8%D0%B5-%D0%B8-%D0%BF%D1%80%D0%BE%D1%84%D0%B5%D1%81%D1%81%D0%B8%D0%BE%D0%BD%D0%B0%D0%BB%D1%8C%D0%BD%D1%8B%D0%B5-%D0%B7%D0%B0%D0%B1%D0%BE%D0%BB%D0%B5%D0%B2%D0%B0%D0%BD%D0%B8%D1%8F-%D0%BB%D0%B5%D0%B3%D0%BA%D0%B8%D1%85/%D1%81%D0%B8%D0%BB%D0%B8%D0%BA%D0%BE%D0%B7). \n\n**Дополнительные исследования** (по показаниям): реакция Манту или проба Пирке для исключения туберкулёза, бронхоскопия для уточнения состояния бронхов и взятия биопсии, исследование лёгочных объёмов и диффузионной способности лёгких (DLCO) и другие [4](https://tradicii-spb.ru/referrals/pulmonology/silikoz/).\n\n## Лечение\n**Силикоз нельзя вылечить** [3](https://fguz-volgograd.ru/component/content/article/2332)[8](https://fguz-volgograd.ru/aktyalnye-temy/237-silikoz). **Основная цель терапии** — торможение прогрессирования фиброзных изменений, предупреждение и устранение осложнений [12](https://www.KrasotaiMedicina.ru/diseases/zabolevanija_pulmonology/silicosis). \n\n**Некоторые меры лечения**: \n* **Медикаментозная терапия**: противовоспалительные и антиоксидантные препараты, антифибротические средства, иммуномодуляторы, глюкокортикостероиды (в тяжёлых случаях) [4](https://tradicii-spb.ru/referrals/pulmonology/silikoz/). \n* **Физиотерапия**: ингаляции с протеолитическими ферментами, ультрафиолетовое облучение грудной клетки — для замедления фиброза [4](https://tradicii-spb.ru/referrals/pulmonology/silikoz/). \n\n**При подтверждении диагноза** первоочередная мера — прекращение контакта с кварцевой пылью [12](https://www.KrasotaiMedicina.ru/diseases/zabolevanija_pulmonology/silicosis).","linksData":[{"sourceId":1,"url":"https://ru.ruwiki.ru/wiki/%D0%A1%D0%B8%D0%BB%D0%B8%D0%BA%D0%BE%D0%B7","shownUrl":"https://ru.ruwiki.ru/wiki/%D0%A1%D0%B8%D0%BB%D0%B8%D0%BA%D0%BE%D0%B7","title":"Силикоз — 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